Tremors are common in individuals with Parkinson but is rare in #ProgressiveSupranuclear Palsy . #Premilife Dr. #RicardoKotliroff
There are similarities between #ProgressiveSupranuclear Palsy and Parkinson disease you should take note of, including beginning in late middle age, slow movement, and rigidity of muscles. #Premilife Dr. #RicardoKotliroff
Eye movements are not normal in #ProgressiveSupranuclear Palsy but close to normal in #Parkinson disease. #Premilife Dr. #RicardoKotliroff
Speech and swallowing difficulties are much more common and severe in #ProgressiveSupranuclear Palsy than in Parkinson’s disease and it shows up earlier in the course of the disease.#Premilife Dr. #RicardoKotliroff
People with #ProgressiveSupranuclear Palsy usually stand straight at times and even tilt their heads backward, though they tend to fall backward. This is known as axial rigidity. #Premilife Dr. #RicardoKotliroff
Both #ProgressiveSupranuclear Palsy and the disease of #Parkinson cause rigidity, difficulty in movement, and clumsiness, but progressive supranuclear palsy is more rapidly progressive as compared to that of Parkinson.
The only proven risk for #ProgressiveSupranuclear Palsy is age. The condition typically affects people around the age of 60 and it does not affect people under the age of 40.
#ProgressiveSupranuclear Palsy Magnetic Resonance Imaging (MRI) is usually done to out rule other illness. In advanced cases, Magnetic Resonance Imaging shows a characteristic reduction in midbrain size#Premilife
Another possible cause of #ProgressiveSupranuclear palsy is cellular damage caused by free radicals, reactive molecules produced by all cells during the process which food is changed into energy in the body. #Premilife
#PSP causes-possibility is that exposure to some unknown substance, a chemical in the food, air, or water can slowly damage some certain vulnerable areas of the brain#Premilife #Dr.RicardoKotliroff
Prion, an abnormal form of a normally harmless protein found in the brain that is responsible for a variety of fatal neurodegenerative diseases, and marked by the development of porous brain tissue and premature dementia
The accumulation of tau puts # PSPin a group of disorders called the tauopathies, which also includes other disorders such as Alzheimer’s disease, corticobasal degeneration, and some forms of frontotemporal degeneration.
#PSP-The hallmark of this disease is the accumulation of abnormal deposits of the protein tau in nerve cells in the brain, an abnormally phosphorylated tau protein so the cells do not work properly and die. #Premilife
#PSP-There is a central theory in many #NeurodegenerativeDiseases that once the unusual aggregates of #proteins like #tau form in a #cell, they can affect a linked cell to also form the protein clumps. #Premilife
#ProgressiveSupranuclear palsy, Genetic, Microtubules help cells maintain their shape, help in cell division, and are important for the transport of materials within cells and to transmit information to other nerve cells.
#ProgressiveSupranuclear palsy, Genetic, Protein tau is linked with microtubules, the structures that support a nerve cell’s long processes that transmit information to other nerve cells. #Premilife #Dr.RicardoKotliroff
#ProgressiveSupranuclear palsy Genetic cause from a change in the MAPT gene, which gives faulty instructions for making tau to the nerve cell. Tau proteins are proteins that control or stabilize microtubules in the cell
Aspiration can develop into #pneumonia, which is the leading cause of death in people with Progressive Supranuclear palsy. To avoid the dangers of choking, a feeding tube may be recommended.Premilife- Dr.Ricardo Kotliroff
Aspiration can develop into #pneumonia, which is the leading cause of #death in people with #ProgressiveSupranuclear palsy #Premilife- Dr.RicardoKotliroff
#ProgressiveSupranuclear palsy complications, Aspiration pneumonia is caused by the inability to control the muscles of the throat. This inability can lead to severe swallowing difficulties #Premilife
#ProgressiveSupranuclear palsy complications, Problems focusing your eyes, which also can lead to injuries, Sleeplessness, Problems looking at bright light. #Premilife- Dr.RicardoKotliroff
#ProgressiveSupranuclear palsy complications, Falling, which could lead to head injuries, fractures, and other injuries. #Premilife- Dr.RicardoKotliroff
#ProgressiveSupranuclear palsy You are also likely to experience depression and anxiety, and a surprised or frightened facial expression, resulting from tough facial muscles. #Premilife- Dr.RicardoKotliroff
#ProgressiveSupranuclear palsy-Dementia, this is a disorder that affects the brain and memory and makes one gradually lose the ability to think, reason, and behave normally.#Premilife- #DrRicardoKotliroff
#ProgressiveSupranuclear palsy symptoms, #loss of interest in fun activities, difficulties with #memory, #reasoning, #ProblemSolving and #DecisionMaking. #Premilife- #DrRicardoKotliroff
#ProgressiveSupranuclear palsy symptoms, #Resting tremors, aversion to bright light or #fear of light, or #photophobia a painful sensitiveness to strong light, #sleep disturbances #Premilife- #DrRicardoKotliroff
#ProgressiveSupranuclear symptom: #Pseudobulbar #palsy, you may likely experience involuntary crying or laughter and pathological #grimacing at odd times, at times following little or no stimulation at all #Premilife
#ProgressiveSupranuclear symptom: Pseudobulbar palsy, a spastic weakness of the lower cranial nerve muscles can also affect your ability to speak, eat, and swallow. #Premilife #DrRicardoKotliroff
#ProgressiveSupranuclear symptom: #Pseudobulbar palsy, a #spastic weakness of the lower #CranialNerve muscles V, VII, and IX through XII may be noticed on examination, with accompanying #dysarthria. #Premilife
#ProgressiveSupranuclear palsy symptom-Pseudobulbar palsy, an uncontrollable emotional expression disorder, is a condition that affects your ability to control the muscles in your in your tongue and throat. #Premilife- #DrRicardoKotliroff
#ProgressiveSupranuclear palsy symptom-Pseudobulbar palsy, an uncontrollable emotional expression disorder, is a condition that affects your ability to control the muscles in your face, not excluding your jaw. #Premilife
#ProgressiveSupranuclear palsy symptom-Problems with swallowing. Dysphagia is difficulty or discomfort in swallowing. #Premilife- #DrRicardoKotliroff
#ProgressiveSupranuclear palsy symptom-Problems with speech. Dysarthria is the difficult articulation of speech that is otherwise linguistically normal, with emotional lability. #Premilife- #DrRicardoKotliroff
#ProgressiveSupranuclear palsy symptom-Progressive axial dystonia. Dystonia can affect one muscle or the entire body. #Premilife- #DrRicardoKotliroff
#ProgressiveSupranuclear symptom, Progressive axial dystonia, this contraction causes the affected body part to twist uncontrollably, resulting in repetition of movements or abnormal postures.#Premilife
#ProgressiveSupranuclear palsy symptom, Progressive axial dystonia, is an illness of movement in which a person’s muscles contract involuntarily. #Premilife- #DrRicardoKotliroff
#ProgressiveSupranuclear palsy symptom, Muscular stiffness, this condition can affect the muscles in the body, causing sharp pain that makes it difficult to move. #Premilife- #DrRicardoKotliroff
#ProgressiveSupranuclear palsy symptom, #MuscularStiffness is one of the most common causes of muscle pain you may experience. It’s characterized by the inability of the muscles to relax without force #Premilife-
#ProgressiveSupranuclear palsy symptom, Bradykinesia, a sluggishness or slowness of movement. Bradykinesia is sometimes linked to an impaired ability to adjust the position of the body. #Premilife- #DrRicardoKotliroff
A symptom of #ProgressiveSupranuclear palsy is #stiffness and #AwkwardMovements. #Premilife- Dr. #RicardoKotliroff
#ProgressiveSupranuclear palsy- Signs of #ProgressiveSupranuclear palsy differ and may imitate that of Parkinson. These signs deteriorate as the disease progresses.#Premilife- Dr. #RicardoKotliroff
#ProgressiveSupranuclear palsy- Voluntary vertical movement of the eyes is difficult, but reflexive eye movements are not affected. #Premilife- Dr. #RicardoKotliroff
#ProgressiveSupranuclear palsy- you may experience is difficulty looking up or down without moving the neck or problems with climbing up and down stairs. #Premilife- Dr. #RicardoKotliroff
#ProgressiveSupranuclear palsy- An inability to aim your eyes properly, this problem with focusing the eyes can make someone look uninterested in conversation due to poor eye contact. Premilife- Dr. #RicardoKotliroff
#ProgressiveSupranuclear palsy-symptom, an inability to aim your eyes properly, it is hard to look downward, or you may experience unclear, dim, and double vision.#Premilife- Dr. #RicardoKotliroff
#ProgressiveSupranuclear palsy-A symptom of #ProgressiveSupranuclear palsy is a sudden loss of balance. While walking, falling backward may occur very early in the disease.#Premilife- Dr. #RicardoKotliroff
#Progressive supranuclear palsy- causes damage to voluntary eye movements, and it usually begins in late middle age #Premilife-Dr. Ricardo Kotliroff
Of every 100,000 people in the world, only see three to six people have #Progressive supranuclear palsy #Premilife-Dr. Ricardo Kotliroff
#PSP- area affected-Brain, our cognitive skills depend on their functioning, such as comprehension, and problem-solving, emotional expression, sexual and social behavior, as well as motor functions #Premilife-Dr. Ricardo Kotliroff
#PSP- area affected-Brain, our cognitive skills depend on their functioning, such as spontaneity, memory, language, judgment, control of impulses. #Premilife-Dr. Ricardo Kotliroff
#PSP- area affected- The spinal cord, particularly the area where part of the bladder and bowel control resides. #Premilife-Dr. Ricardo Kotliroff
#PSP- area affected- #The dentate nucleus of the cerebellum, responsible for the planning, initiation, and control of voluntary movements. #Premilife-Dr. Ricardo Kotliroff
#PSP- area affected- #CerebralCortex, particularly the frontal lobes. A control center for different aspects of our ability to communicate and our personality. #Premilife-Dr. Ricardo Kotliroff
#PSP-Brain area affected-the #BasalGanglia, responsible for the performance of executive functions, #learning, #MotorControl, #emotions, and #behavior. #Premilife-Dr. Ricardo Kotliroff
#ProgressiveSupranuclear palsy-Area affected: the brainstem, particularly the part of the midbrain where the supranuclear”eye movement resides. #Premilife Dr. #RicardoKotliroff
#ProgressiveSupranuclear palsy deteriorates (progressive) and causes weakness (palsy) by harming certain parts of the brain above nerve cell clusters which are known as nuclei supranuclear #Premilife-Dr. Ricardo Kotliroff
#ProgressiveSupranuclear palsy, this illness is a result of degeneration of the cells in areas of your brain that control body movement and thinking. #Premilife-Dr. Ricardo Kotliroff
#ProgressiveSupranuclear palsy, Steele-Richardson-Olszewski syndrome, is a rare brain illness believed to be the cause of serious problems with walking, balance, and movement of the eyes. #Premilife-Dr. Ricardo Kotliroff
#MacularDegeneration-In current and ex-smokers β-carotene can inflate the danger of lung cancer. Recently substitution of β-carotene with lutein plus zeaxanthin has been discovered to have comparable efficacy #Premilife-
OCT (Optical coherence tomography) also helps identify subretinal and intraretinal fluid and can aid to assess response to treatment. #Premilife-Dr. Ricardo Kotliroff
Another sign of #MacularDegeneration is the appearance of pigmentary changes under the retina. #Premilife-Dr. Ricardo Kotliroff
Many people have some very small drusen as a usual part of aging. #MacularDegeneration is indicated by the presence of medium-to-large drusen. #Premilife-Dr. Ricardo Kotliroff
#MacularDegeneration-#Optical coherence tomography, during the test, your eye care physician looks for drusen, which are usually yellow deposits under the retina. #Premilife-Dr. #RicardoKotliroff
#MacularDegeneration-#Optical coherence tomography (OCT) uses light waves and can achieve very high-resolution images of any tissues penetrable by light like the eyes. #Premilife-Dr. #RicardoKotliroff
#MacularDegeneration-#Ultrasound uses sound waves to capture images of living #tissues like the #eyes. #Premilife-Dr. #RicardoKotliroff
#MacularDegeneration-Angiography characterizes and shows subretinal choroidal neovascular membranes and the areas of geographical atrophy can be delineated. #Premilife-Dr. Ricardo Kotliroff
#MacularDegeneration-Visual changes can, at times, be detected with an Amsler grid. Changes in your central vision can trigger the lines in the grid to appear or disappear wavy. #Premilife-Dr. Ricardo Kotliroff
Both forms of #MacularDegeneration are diagnosed with funduscopic examination. #Premilife-Dr. Ricardo Kotliroff
#MacularDegeneration is usual among whites and affects individuals of European descent more rapidly than African Americans in the United States. #Premilife-Dr. Ricardo Kotliroff
A diet rich in fatty acids and omega-3 such as Japanese food or incorporating fish such as salmon, mackerel, sardines, prickly pear, and herring into the diet may decrease the risk of developing #MacularDegeneration.
Studies based on the prevalence of result have come up with the suggestion that cataract surgery increases the progression of #MacularDegeneration, but is hard to know the difference between causation and association.
Many epidemiological studies have come up with the suggestion that cataract surgery increases the progression of #MacularDegeneration. #Premilife-Dr. Ricardo Kotliroff
The effect of cataract surgery on #MacularDegenerationis more controversial and the outcome of the different research is not consistent. #Premilife-Dr. Ricardo Kotliroff
#MacularDegeneration-Obesity linked to #MacularDegeneration risk may be via indirect effects on changes in zeaxanthin and lutein status and metabolism. #Premilife-Dr. Ricardo Kotliroff
#MacularDegeneration-Usually, the lens focuses all the colors in the same convergence point; there is a situation called chromatic aberration where there is a dispersion of colors. #Premilife-Dr. Ricardo Kotliroff
#MacularDegeneration-Lutein and zeaxanthin may prevent eye disease because they absorb damaging blue light, as it has an oxidative photo effect that damages the macula. #Premilife-Dr. Ricardo Kotliroff
#MacularDegeneration-The physiologic changes described in obesity may lead to high destruction and a lowered circulatory delivery of zeaxanthin and lutein to the macula. #Premilife-Dr. Ricardo Kotliroff
#MacularDegeneration-Lutein and zeaxanthin are two major carotenoids found in the human macula and retina. They are the macula pigments and are five times more concentrated in the macula than in the peripheral retina.
#MacularDegeneration-Obesity causes inflammation. Inflammation is intended to eliminate foreign or damaged material and to signal to other cells that there is a danger so they can initiate a broader immune response.
#MacularDegeneration-In obesity changes in the levels of total cholesterol, triglycerides, high-density lipoprotein, low-density lipoprotein, and cholesterol affect the macula negatively. #Premilife-Dr. Ricardo Kotliroff
#MacularDegeneration-Oxidative stress is a disturbance in the balance between the production of reactive oxygen species, which are free radicals, and antioxidant defenses. #Premilife-Dr. Ricardo Kotliroff
The means by which #MacularDegeneration is increased by obesity is linked to the physiologic changes occurring with this condition: oxidative stress, changes in the lipoprotein profile, and inflammation #Premilife
Obesity increases the risk of having late #MacularDegeneration by 32%. #Premilife-Dr. Ricardo Kotliroff
#MacularDegeneration-Many studies have shown that high blood pressure is associated with a reduced choroidal flow of blood and disturbed vascular homeostasis in these patients. #Premilife-Dr. Ricardo Kotliroff
There is an involvement of hypertension in #MacularDegeneration on the other hand there is no data that successful management of hypertension and antihypertensive medication have a positive effect on its clinical outcome
#MacularDegeneration is surrounded by abnormal #neovascularization, to which #angiotensin II and #GrowthFactors make a big contribution. #Premilife-Dr. Ricardo Kotliroff
The involvement of hypertension in the pathogenesis of # MacularDegeneration has been well treated in literature since its first appearance. #Premilife-#DrRicardoKotliroff
Hemodynamic abnormalities contribute to #MacularDegeneration with the renin-angiotensin system, a hormone system that specializes in regulating fluid balance and blood pressure playing a vital role #Premilife
Recent data postulates #Macular Degeneration may independently predict coronary heart disease or stroke over the long term in persons aged between 49 and 75 years. #Premilife-#DrRicardoKotliroff
#VascularDisease and #MacularDegeneration share related risk factors, such as high increase levels of #cholesterol, #triglyceride levels, and #HDL cholesterol. #Premilife-Dr. #RicardoKotliroff
Smoking has also been revealed to lower #macular pigment optical density, which projects the levels of the protective #carotenoids, zeaxanthin, and lutein in the macular #retina. #Premilife-Dr. #RicardoKotliroff
Smoking may lower the #choroidal flow of blood in the #eye and promote #ischemia, #hypoxia, and #micro-infarctions, all of which may inflate the susceptibility of the #macula to degenerative changes. #Premilife
#MacularDegeneration reflects compiled oxidative damage in the retina. #Premilife-Dr. #RicardoKotliroff
Although the mechanism of action and the pathogenesis of smoking on the eye are not clear enough, the risk of having #Macular Degeneration in smokers may involve more than one mechanism#Premilife-Dr. Ricardo Kotliroff
There was evidence that ex-smokers had a decreased risk having of #Macular Degeneration, suggesting reversibility of effect. #Premilife-Dr. Ricardo Kotliroff
A demonstration of dose-response verified the risk of having #Macular Degeneration doubles as the intensity of smoking increases.
Though it depends on the type of #Macular Degeneration, the risk of current-smokers having the disease is two or three times the risk for never-smokers. #Premilife-Dr. Ricardo Kotliroff
#Macular Degeneration Those who are at risk should advise siblings and children to seek proper ophthalmological advice in case they develop visual signs of distortion or decreased vision. #Premilife-Dr. Ricardo Kotlirof
#Macular Degeneration risk is increased by having an affected first-degree relative. #Premilife-Dr. Ricardo Kotliroff
Studies described a genetic risk factor related to changes in the long (q) arm of chromosome 10 in a region called 10q26. That change is also linked to a high risk of developing #Macular Degeneration Dr. Ricardo Kotliroff
Homozygous individuals have an approximately sevenfold increased chance of developing#Macular Degeneration, while heterozygotes have a two-to-threefold increased likelihood of developing the disease. #Premilife
When the two genes, one from the father and the other from the mother, have the same information we call them homozygous. When they have different information they are called heterozygous. #Premilife-Dr. Ricardo Kotliroff
#Macular Degeneration-Genes are responsible for our characteristics; for example #height, #eye color, normal #vision versus #blindness to colors, etc. #Premilife-Dr. Ricardo Kotliroff
#Macular Degeneration-Humans have 46 chromosomes. 23 from the father and 23 from the mother. We also have two copies of each gene, one from the father and the other from the mother. #Premilife-Dr. Ricardo Kotliroff
#Macular Degeneration- The complement factor H prevents infection; it also attacks diseased, dysplastic cells and spares cells that are healthy. #Premilife-Dr. Ricardo Kotliroff
Studies implicated activation of complement factor H in the formation of drusen, the hallmark lesion of #Macular Degeneration. #Premilife-Dr. Ricardo Kotliroff
#Macular Degeneration-The complement factor H enhances and complements the ability of antibodies and phagocytic cells to clear microbes and damaged cells from an organism #Premilife-Dr. Ricardo Kotliroff
#Macular Degeneration-The complement factor H is part of the complement system that consists of a number of small proteins found in the blood and is a part of the immune system Dr. #RicardoKotliroff
#Macular Degeneration-The gene for complement factor H is located on chromosome 1 in a region called q31 and provides the coded instructions for the synthesis of the protein complement factor H. Dr. #RicardoKotliroff
Complex research identified 20 chromosomal regions as a harbor for genetic variants associated with #Macular Degeneration. #Premilife-Dr. Ricardo Kotliroff
Pioneering discovery in 2005 of complement factor H (CFH) as a significant #Macular Degeneration susceptibility gene. #Premilife-Dr. Ricardo Kotliroff
#Macular Degeneration-In the general population, the genetic risk is 23%, increasing to 45% in twins. #Premilife-Dr. Ricardo Kotliroff
#Macular Degeneration-Genes that code for defective proteins for good cholesterol, whose function is to transport cholesterol. When they are abnormal the bad cholesterol increases #Premilife-Dr. Ricardo Kotliroff
#Macular Degeneration #polymorphisms are in the genes that code for defective proteins for high-density lipoproteins or good cholesterol, whose function is to transport cholesterol. #Premilife
#Apoptosis is a genetically determined process by means of which the DNA of a cell is damaged, and the fragmentation is activated leading to the elimination and death of pathological and unwanted cells. Premilife
#Macular Degeneration #The cell lysis is the disintegration of a cell by rupture of the cell wall or membrane which leads to its death. Premilife-Dr. Ricardo Kotliroff
#Macular Degeneration #Phagocytosis is a process in which cells like neutrophils engulf microorganisms, cell debris, harmful particles and eliminates them Premilife-Dr. Ricardo Kotliroff
#Macula-The inflammatory response occurs when the tissues of the body are attacked. Then, the damaged cells release chemical substances such as #prostaglandins, #histamine, and #bradykinin. Premilife-Dr. Ricardo Kotliroff
The defensive response comprises a complement system that facilitates important processes such as the inflammatory response, #phagocytosis, #cell lysis, and #apoptosis. Premilife-Dr. Ricardo Kotliroff
When microorganisms such as bacteria, viruses, or protozoa attack the organism, a defensive immune response occurs against the hostile agent. #Premilife-Dr. Ricardo Kotliroff
In #Maculardegeneration are genes that encode defective proteins of the complement cascade pathway, an essential biochemical process that helps cells of the immune system to eliminate bacteria and viruses. #Premilife
The complement cascade pathway, an essential biochemical process that helps or complements cells of the immune system to eliminate bacteria, viruses, and other invading pathogens. Premilife- Dr. Ricardo Kotliroff
#MacularDegeneration, In our body, #proteins have a central role in the normal function, structure, and regulation of all #biological process.#Premilife-Dr. #RicardoKotliroff
When we have a mutant gene, the protein coded by this gene is defective, and the set of processes that the protein controls is now pathological,these pathological processes lead to the development of macular degeneration.
Single nucleotide polymorphisms are the most common genetic error in #MacularDegeneration. Errors are changes of a single nucleotide at a particular position in the DNA strand, for example, thymine instead of cytosine.
In #MacularDegeneration, the contribution support for #genetics is incontrovertible and it comes from both classical #epidemiological and twin studies and gene-mapping studies. #Premilife-Dr. #RicardoKotliroff
#MacularDegeneration . The #Gen encodes a functional product, #proteins for example. #Premilife-Dr. #RicardoKotliroff
#MacularDegeneration The gen is the molecular information unit of genetic inheritance, and they occupy a fixed position in the chromosomes that we call locus. Premilife-Dr. Ricardo Kotliroff
DNA contains our genetic code and is found in the cell nucleus and the mitochondria of each cell of our organism where it is organized into structures called chromosomes. Premilife-Dr. Ricardo Kotliroff
#MacularDegeneration All organisms develop and reproduce thanks to a molecule-deoxyribonucleic acid or DNA. DNA is transmitted from parents to children. Premilife-Dr. Ricardo Kotliroff
All organisms develop and reproduce thanks to a molecule-DNA; we call it the molecule of life since it contains the necessary instructions to make this process possible. Premilife-Dr. Ricardo Kotliroff
When genetic risk and environmental causes such as smoking or diet align with increasing age, the pathological changes of #MacularDegeneration becomes even likelier. Premilife – Dr. Ricardo Kotliroff
Some risk factors associated with #MacularDegeneration are #Obesity, Previous #cataract surgery, A diet low in #Omega-3 fatty acids, #Race/Ethnicity, #Sex. Premilife – Dr. Ricardo Kotliroff
The dominant cause of, severe, irreversible loss of vision in people over the age of 60 is #MacularDegeneration and disease prevalence for late macular degeneration is almost 10% in people over age 80. Premilife
Some risk factors associated with #MacularDegeneration are #Age, #Genetic variants, #Family history, #Smoking, #CardiovascularDisease #Hypertension, Premilife – Dr. Ricardo Kotliroff
A sudden visual loss in patients with exudative #MacularDegeneration occurs at the time of pigment epithelial or sensory retinal detachment or hemorrhage from a subretinal neovascular membrane. Premilife Dr. R.Kotliroff
Wet #MacularDegeneration normally affects one eye at a time; hence symptoms of wet #MacularDegeneration are at times unilateral. #Premilife – Dr. Ricardo Kotliroff
Shallow color and #vision are not affected; however, the patient may legally become #blind (< 20/200 vision) in the affected eye, especially if the #MACULARDEGENERATION is not treated.
#MacularDegeneration, #visual distortion is usually the first symptom, such as #scotoma which is a central #blind spot, or #metamorphopsia which means curving of straight lines. #Premilife – Dr. Ricardo Kotliroff
Quick #VisionLoss, normally over days to weeks, is frequent in Wet #MACULARDEGENERATION. #Premilife – Dr. Ricardo Kotliroff
Wet #MacularDegeneration. The exudative form accounts for about 90% of all cases of legal blindness due to this disorder. #Premilife – Dr. Ricardo Kotliroff
Wet #MacularDegeneration. In exudative degeneration, the #visual loss is of more rapid onset and greater severity, and the two #eyes are frequently affected sequentially over a period of a few years. #Premilife
Dry #MacularDegeneration In tasks where the distinction of fine details is essential as in reading, handling, or face recognition, more light is needed. #Premilife-Dr. #RicardoKotliroff
In dry #MacularDegeneration Straight lines are distorted and appear bent. Loss of visual acuity and sensitivity to the contrast between objects is lost. #Premilife-Dr. #RicardoKotliroff
In dry #MacularDegeneration the loss of central #vision happens over the years and is not painful; many patients hold on to vision enough to drive and read. #Premilife-Dr. #RicardoKotliroff
Wet #MACULARDEGENERATION happens when new, abnormal #BloodVessels develop under the #retina in a process called #choroidal #neovascularization, i.e., the formation of a new abnormal #vessel#Premilife #DrRicardoKotliroff
One-third of wet #MacularDegeneration patients present geographic atrophy. #Premilife-Dr. #RicardoKotliroff
As #MacularDegeneration progresses, we see atrophic degeneration with severe thinning of the #retina, death of cells in the retinal pigmentum epithelium, severe thickening of the #Bruch’s membrane and #arteriosclerosis
#MacularDegeneration. If we analyze the composition of the drusen, we found an accumulation of lipoproteins and lipids, complement, inflammatory proteins, and amyloids, among others. #Premilife-Dr. #RicardoKotliroff
Soft #drusen are associated with the development of exudative age-related #MacularDegeneration.. #Premilife-Dr. #RicardoKotliroff
#MacularDegeneration. A more serious form is when soft drusen appear. They look like large white spots, are confluent, paler, and lead to a thinner retina called geographic atrophy. #Premilife-Dr. #RicardoKotliroff
#MacularDegeneration. The compilation of more catabolites or waste products from the cones and rods leads to larger, hard drusen #Premilife-Dr. #RicardoKotliroff
#MacularDegeneration. There are different types of drusen. When there are few waste products, the drusen form small white dots that do not affect the vision. #Premilife-Dr. #RicardoKotliroff
#MacularDegeneration. The retinal pigment epithelium plays a vital role in keeping the photoreceptors – cones and rods- healthy and functioning correctly. #Premilife-Dr. #RicardoKotliroff
The pigment epithelium of the retina and the Bruch’s membrane are barriers that maintain the integrity between the choroid and the retina and allow the flow of chemicals to photoreceptors and disposal of waste products.
Arteriosclerosis is a vascular alteration where the arteries harden, lose elasticity, and increase in thickness. #Premilife-Dr. #RicardoKotliroff
As in the rest of the body’s organs, older people will have changes in the #eyes related to aging. Among these changes we find arteriosclerosis in the blood vessels of the choroidal region #Premilife-Dr. #RicardoKotliroff
The precursor of #MacularDegeneration is age-related #maculopathy, of which the hallmark is the development of retinal #drusen that, while not the cause, increase the risk of #MacularDegeneration.
Although both types Dry and Wet #MacularDegeneration are progressive and usually bilateral, they differ in manifestations, prognosis, and management. #Premilife-Dr. #RicardoKotliroff
Wet, also known as neovascular or exudative: Wet MACULAR DEGENERATION happens in about 15% of people. #Premilife-Dr. #RicardoKotliroff
About 85% of people with #MacularDegeneration only have the dry form; it’s the most common and the least severe, and it will develop more slowly. #Premilife-Dr. #RicardoKotliroff
Age-related #MacularDegeneration includes a broad spectrum of clinical and pathological findings that can be classified into two groups, #Dry and #WetMacular Degeneration.
The #visual system detects and interprets information from visible light to build a representation of the #environment. #Premilife-Dr. #RicardoKotliroff
The #visual system in synthesis is a part of the central #NervousSystem centered on giving organisms the ability to process visual detail and enables the formation of many non-image photo response features. #Premilife
Vision is the ability to interpret light waves from the sun and are in the visible spectrum for us or between violet light 400 nanometers to red light 800 nanometers-a small part of the electromagnetic spectrum #Premilife
In #MacularDegeneration, anatomical structures that allow #vision are damaged. #Premilife-Dr. #RicardoKotliroff
Macular degeneration is a multifactorial disease. It’s caused by the sum of the interaction of many #genes and non-genetic factors. This leads to a process that causes the #neurodegeneration of the #macula. #Premilife
In the United States alone, #MACULARDEGENERATION afflicts almost 10 million individuals-twice the number of #Alzheimer’s disease patients and roughly equal to the total number of all #cancer patients together. #Premilife
Age #MacularDegeneration is the most common cause of irreversible central loss of #vision in elderly patients. #Premilife-Dr. #RicardoKotliroff
Age-related #MacularDegeneration causes the deterioration of the #macula, which is the small central area of the #retina that controls the acuity of visuals and causes #VisionLoss affecting the quality of life. Premilife
#MacularDegeneration. Your ability to read is determined by how healthy the macula is, as well as your ability to recognizing faces, watching television, driving or using a computer. #Premilfe. Dr. Ricardo Kotliroff
#MacularHoles and # MacularDegeneration are two different and distinct conditions. No relationship exists between the two diseases, although they have similar symptoms.
#MacularDegeneration is a condition that affects the tissues under the #retina, while a #MacularHole requires damage from within the eye, at the junction between the vitreous and the retina itself.
MacularHoles and Age-related #MacularDegenerations are two different and distinct conditions. #Premilife – Dr Ricardo Kotliroff
# MacularHole, people may notice that reading and performing other routine tasks with the affected eye becomes hard.#Premilife. Dr. Ricardo Kotliroff
In the early stage of a # MacularHole, people may notice a slight distortion or blurriness in their straight-ahead vision. Straight lines or objects look wavy or bent.
# MacularHoles show up slowly over time, so you may not see signs until your vision is affected. Premilife Dr.Ricardo Kotliroff
The most common sign of # MacularHole is a slow decline in the central vision of the affected eye The length to which vision is affected depends on the location and size of the macular hole, and the stage of its progress.
#MacularHole signs are: Difficulty in detail tasks like reading, Blurred central #vision, Distorted, wavy vision, Central #blind spot or gray area.
#Proliferative #DiabeticRetinopathy. The new blood vessel may leak blood into the vitreous, clouding the vision. #Premilife-Dr.Ricardo #Kotliroff
#Proliferative DiabeticRetinopathy is a more advanced form of the #disease. At this point, new weak blood vessels grow in the #retina and into the #vitreous, the gel-like fluid that fills the back of the eye.
#Hypertensive #retinopathy. Funduscopic examination reveals arteriolar constriction, #vascular wall changes, #arteriovenous nicking, cotton-wool spots, yellow hard exudates, flame-shaped hemorrhages, and optic disk edema.
#MacularHole secondary to Hypertensive retinopathy that is at retinal vascular risk triggered by hypertension.
#MacularHole secondary to Lightning strike injury #Premilife #DrRicardoKotliroff
#MacularHole secondary to High #myopia coupled with posterior #staphyloma, Staphyloma is a protrusion of the #sclera or #cornea, usually lined with uveal tissue, due to #inflammation.
#MacularHole secondary to #BestDisease.#Premilife Dr.Ricardo #Kotliroff
# BestDisease affects only the #eyes, so is not triggered by or linked to a problem or disease in other parts your #body. #Premilife Dr. #RicardoKotliroff
# BestDisease might make this central #vision distorted or blurry and, over a period of time, it may trigger a blank patch in your vision’s center. #Premilife Dr. #RicardoKotliroff
#BestDisease affects the vision you use when looking directly at something, for instance when you’re looking at photos, reading, or watching TV. #Premilife Dr. #RicardoKotliroff
#BestDisease triggers problems with your central #vision but does not lead to absolute loss of #sight and is painless. #Premilife Dr. #RicardoKotliroff
#Best’s #Disease can begin to trigger changes at the back of the #eye between the ages of 3 to 15, although it does not affect your #vision until later in #life. #Premilife Dr. #RicardoKotliroff
#Best’s #Disease is a #genetic disease. You are born with this and have an #autosomal-dominant inheritance characterized by the subretinal compilation of egg-yellowish material in the #macular area.
#Epiretinal #membrane. These membranes are formed by a semi-translucent fibrous material that covers the #macula in the foveal and perifoveal areas making vision difficult. It is also known as a #MacularPucker.
#Epiretinal #membrane. These form in the back of the #eye in response to changes in the #vitreous humor or, more uncommonly, #diabetes. #Premilife #DrRicardoKotliroff
#MacularHole secondary to #Retinal #detachment, happens when #subretinal fluid piles up in the potential space between the #neurosensory #retina and the underlying retinal pigment epithelium.
#MacularHole secondarily induced by a pathological process: In the developed world, #cystoid #macular #edema is the leading cause of the loss of central #vision.
Cystoid #macular edema is a painless disorder which affects the central macula or retina. The loss of vision is due to the damage caused to the photoreceptors by the accumulation of fluid and the thickening of the retina.
#MacularHole due to #Vitreomacular traction syndrome. This is a #vision-threatening condition and can trigger signs ranging from lowered and blurry #vision to distorted and blacked-out central vision. #Premilife
Trauma-related #macular #holes are suspected to be linked to the transmission of concussive force in a contrecoup manner, which leads to the immediate rupture of the #macula at its thinnest point.
#MacularHole secondarily induced by a pathological process: The initially published description of a #macular #hole by Herman Knapp in 1869 was of one in a previously traumatized #eye. #Premilife #DrRicardoKotliroff
A #MacularHole can immediately form after blunt #trauma.#Premilife Dr.#R.Kotliroff
Although the precise #pathogenesis of an idiopathic #macular #hole is still speculative, evidence postulates that abnormal tractional forces of the #vitreous on the #macula are directly responsible.
No evidence has confirmed associations for #SystemicDisorders as a cause for idiopathic #MacularHoles formation. Initial studies implicated #hypertension, #CardiovascularDisease, and prior hysterectomy as possible dangers
As you age, the vitreous degenerate, as a result, it begins to slowly shrink moving away from the surface of the retina. If the traction force is strong enough it triggers a retinal tear or breaks creating a macular hole.
The #climax incidence of #idiopathic #macular #hole development is in the 7th decade of life, and women are more affected than men. #Premilife #DrRicardoKotliroff
The majority of #macular #holes are #idiopathic, meaning they occur in #eyes that have no past #ocular #pathology. It’s typically related to the #vitreous #aging process. #Premilife #DrRicardoKotliroff
If there is a #macular #hole in one eye, there is a 10-15 percent probability a macular hole will develop in your other #eye over your lifetime. #Premilife #DrRicardoKotliroff
A #macular #hole can trigger distorted central #vision and general unclear vision. As this hole increases, a #blind or #dark spot appears in your central vision. #Premilife #DrRicardoKotliroff
The macula gives the bright, central vision you need for driving, reading, and seeing clearly. #Premilife #DrRicardoKotliroff
In many ways, the human #eye works like a digital camera: The #cornea is primarily concentrated by light – which is the clear front part of the eye that acts like a camera #lens. #Premilife #DrRicardoKotliroff
Because of its central importance in the #VisualProcess, the #macular #hole leads to a loss of our #visual capacity. #Premilife #DrRicardoKotliroff
The activity of each #eye is wonderful. They react and adjust according to the amount of light that enters them at every moment with which we will construct an interpretation of the #visual reality surrounding us.
A #MacularHole is a small break in the #macula, found in the middle of the #eye’s light-sensitive tissue known as the #retina. #Premilife #DrRicardoKotliroff
“The preservation of health is a choice and a duty.” – Dr. Ricardo Kotliroff
The activity of each #eye is wonderful. They react and adjust according to the amount of #light that enters them at every moment. #Premilife #DrRicardoKotliroff
When people were surveyed regarding the five #senses – #sight, #hearing, #smell, #touch, and #taste-consistent reports were made that #eyesight is the mode of #perception most valued and which they #fear to lose most.
Everyone knows that #energy is the source of everything in this world, right? But almost no one knows that the energy can beat all kind of diseases. #Premilife #DrRicardoKotliroff
When you know how to insert #energy in your #body, your body can beat any #disease you have and let you feel stronger and greater. #Premilife #DrRicardoKotliroff
“There is one thing that makes everything on the universe to exist, and this one thing can beat any disease in your body – this one thing is called ENERGY.” – Dr. Ricardo Kotliroff
You can’t create #energy. The energy exists all the time and everywhere. The question you need to ask is “how do I insert the energy in my #body?” And that is exactly what we are doing here in the #BodyChargers movement!
We need to insert #energy into the system to stop the process of disintegration and to keep the #body functioning at the level of normal #health. #Premilife #DrRicardoKotliroff
Every closed #physical system loses its #energy from the moment it is #created until it fades and crumbles and becomes part of the still world again. #Premilife #DrRicardoKotliroff
WE FOLLOW THE #UNIVERSE LAW. What we are doing, are based on facts! #Premilife
Our success is happening right now, day after day. It’s happening through the kind of process we like to call #Body Charging. #Premilife
This power is the #ENERGY. We give our #body this energy in the form of #homeopathic treatments with our special #formula. #Premilife
We use a different method, a unique method. We understand what is the power of everything, including the power in our #body. We use this power to defeat #diseases no matter which disease it is. #Premilife
#Body chargers remember the formula: Balanced Energy + Human Body = A healthy and strong body and a body free of #diseases. #Premilife
For #body chargers, even THE SKY IS NOT THE LIMIT. We understand the power of #energy on our #body. We discover the #health formula. We know how to utilize new opportunities. #Premilife
Body chargers are DOING THINGS RIGHT. We give our body what it needs in the form of drinking (water), eating, breathing and exercising properly. We use the right treatment → We use the energetic #treatment. #Premilife
#Body chargers have the POWER. We don’t rely on lack. We don’t let others or things to write our fate, we write our own fate alone. #Premilife
#Body chargers are UNIQUE. We have a unique mindset. We use a unique method to #heal. We try new things.#Premilife
#Body chargers are FIGHTERS. We don’t let the #diseases control our #lives. We will fight until we win. For us, loss is not an option at all. #Premilife
#Body chargers are #healthier people. Energy is life. #Premilife
#Body chargers are SMART. We know that #knowledge is power. We know that to beat our enemies, we need to know them well, so we learn before we act. #Premilife
I am a body charger. I love to live and live the life. Energy is Life. #Premilife
I am a body charger. I take responsibility in my life. Energy is Life. #Premilife
I am a body charger. I have willpower. Energy is Life. #Premilife
Body chargers are UNIQUE. We have a unique mindset. We use a unique method to heal. We try new things. #Premilife
“The present is always a convergence moment of your past and future, choose life and the path to mind and body health becoming an energetic body charger. Choose your way and stay true to yourself” – Dr. Ricardo Kotliroff
“Energy + Body = A Healthy and Strong body.” – #DrRicardoKotliroff #Premilife
“There is no more violent death than sadness, choose life and a Body charger mind. Choose your own path and always look forward!” – #DrRicardoKotliroff
Give your #body the #energy it needs and it gives you back #health and strength
You just need to give your #body the tool it needs to #heal and this tool is the #ENERGY. #Premilife #DrRicardoKotliroff
Being chronically #ill-You can’t dwell on questions like. ‘Why is this happening to me?’ or ‘What if it gets worse? Dealing with the cycle of ‘good days’ and ‘bad days’.
When you suffer from a chronic #disease, you must face the demands of the disease with the requirements of your everyday #life, coping every day with #nutrition demands, #medication management, and #self-care management
If you suffer from #anxiety or #stress, they can progress into #insomnia, full-on #depression, tension #headaches, and chronic #pain conditions.
When you suffer from a chronic #disease, you must face and balance the demands of the disease with the needs of your daily #life, coping every day challenges such as #depression, #anxiety, #chronic pain, and #fatigue.
If you have #diabetes, you may have associated problems with your #nerves, #eyes, and #kidneys.
In #Premilife, we want you to be ready to make #positive #choices and feel strong enough #mentally to battle the #disease.
Premilife homeopathic formula specifically targets mental health and your emotional and social sense of wellness.
In #Premilife, we want to help you reach the quality of life you truly deserve.
In #Premilife, We want you to feel and be more functional
In #Premilife, We want to reduce the number of #complications you suffer. We want to extend your #life.
In #Premilife, We want to reduce the #signs and #symptoms of your #illness
In #Premilife, We want to see your #condition addressed with the best possible #clinical outcome, achieved efficiently.
In #Premilife, We want to boost the #energy levels within your #body and combat the issues that came along with your #illness.
In #Premilife, We want to change the way you #feel about your #illness. Less #stress. Less #anxiety. Greater #positivity. #Premilife #DrRicardoKotliroff
The center of our philosophy is that your body contains an #energetic balance and that #illness comes when something disrupts that balance. Restoring the balance will restore your #health.#Premilife #DrRicardoKotliroff
“You exist as a whole, so why treat you as a part?” – Dr. Ricardo Kotliroff
“We passionately believe that illness is best treated by an approach that focuses on healing the body, mind and spirit together.” – Dr. Ricardo Kotliroff
“You don’t deserve your illness. It’s not your fault and you should not accept it. You have the ability to heal.” – Dr. Ricardo Kotliroff
The purpose of this #webinar isn’t just to tell you that there’s another way of treating your condition, it’s to tell you that you’re not alone. #Premilife #DrRicardoKotliroff
You need a #homeopathic formula that takes into account the #genetic and #pathological processes that #diseases follow inside your body. #Premilife #DrRicardoKotliroff
You need a #mind strong and #positive enough to make the right #emotional #choices about how you face your #illness. #Premilife #DrRicardoKotliroff
To win any #disease you have to give your #body the right tools for the battle. You need the #energy levels within your body to be in the right balance. #Premilife #DrRicardoKotliroff
The purpose of #Premilife is to give life back to #people, providing them the best of our #knowledge to overcome #illnesses and enjoy recovered #health. #DrRicardoKotliroff
“Some people say that one of the greatest moments in life is when you discover your true purpose.” – #DrRicardoKotliroff
#Premilife treatments are designed to give your #body the #energy it needs. For you, that means giving it the energy it needs to overcome your #disease. #Premilife #DrRicardoKotliroff
When you look at our testimonials, what you’ll see is a collection of real-life accounts about how Premilife has impacted our patients and have radically changed their lives by allowing them to manage their health.
We choose a #homeopathic approach by its compatibility with other #treatments. #Premilife’s homeopathic remedies are used along with prescribed medications because they will not interact #Premilife #DrRicardoKotliroff
Our formulas are based on #Genetics, #MolecularBiology, #Chemistry, #EnergeticMedicine, and #QuantumPhysics along with the knowledge of how #diseases are caused in the first place. #Premilife #DrRicardoKotliroff
Our #knowledge extends to both #biological and #psychiatric aspects and also looks at how various #environmental factors might affect a person’s #symptoms. #Premilife #DrRicardoKotliroff
#Homeopathic formulas-We acquire this knowledge from the fields of #Genetics, #Molecular #Biology, #Chemistry, #Energetic Medicine, and #Quantum Physics, as well as from the #symptoms of a disease itself. #Premilife
#Homeopathy works by lessening the severity of the #symptoms and by enabling the #body to do its own #healing work. #Premilife #DrRicardoKotliroff
#Homeopathic #therapy is an effective and natural way to combat #diseases. The history of its use dates back over 200 years. #Premilife #DrRicardoKotliroff
I started creating #homeopathic #remedies that came from the same basic idea as #acupuncture and use the #energy laws’ of #health and #disease to develop those formulas. #Premilife #DrRicardoKotliroff
How do you provide plants with the #energy they need? By the #sun! How do you provide your cell phone with the energy it needs? By a charger! And how do you provide your #body with the energy it needs? #Premilife
Just think about your #body like a plant, if you wish your plant to grow, you need to provide the #energy it needs. Without solar energy, it would just #die! #Premilife #DrRicardoKotliroff
“Look at all the living creature, vegetation, and inanimate that you can think of, everyone needs energy”. – Dr.Ricardo Kotliroff
“I saw that everything in this world needs energy to exist and without energy our entire world would simply disappear.” – Dr. Ricardo Kotliroff
“Every disease can be understood, resisted and defeated; life has more power than death.” -Dr. Ricardo Kotliroff
The lack of energy leads to the defeat of your body and mind. The restoration of energy leads to the only desirable victory: the recovery of your health.” – Dr. Ricardo Kotliroff
“Sources of energy are movement, collective work, rest, dreams and positive relationships with other people in the social environment.” – Dr. Ricardo Kotliroff
“It is useless for you to try to hide the wounds that have not healed or the passions that burn and damage your soul. Energy can restore what was lost.” – Dr. Ricardo Kotliroff
“When you confront human poverty, sickness, and melancholy, human energy is the best remedy.” – Dr. Ricardo Kotliroff
“The energy and the matter of your body and your soul are your best doctor.” – Dr. Ricardo Kotliroff.
“By treating the energetic imbalance and the cause of the illness, you have a better chance of reverse the disease’s ability to change your body and weak your mind.” – Dr. Ricardo Kotliroff.
“Energy is the king of victory. Because mental and physical illnesses are defeat and health is victory, we embrace the energy of life that leads to the triumph of health over disease” – Dr. Ricardo Kotliroff
“Human choices build destiny; they can be negative and set the path to disease or create beautiful choices that lead to a healthy and meaningful life.” Dr. Ricardo Kotliroff
“Dealing with illness can drain you psychologically and emotionally, but energy can empower your state of mind and build the path to restore your emotional strength.” – Dr. Ricardo Kotliroff
“Energy is eternal and your body cannot be successful in its fight against diseases without it.” – Dr. Ricardo Kotliroff
#Cigarette #smoking, #lethargy, excessive #drinking, and poor #diet all boost your chances of developing a chronic “noncommunicable” #disease.
#Cardiovascular illness, #cancer, #respiratory illness, and #diabetes are responsible for over 80% of all noncommunicable premature deaths. That’s a LOT. #Premilife #DrRicardoKotliroff
The most common cause of #death is #cardiovascular illness. That alone kills just short of eighteen million people annually. #Premilife #DrRicardoKotliroff
“Noncommunicable” diseases are responsible for over 41 million deaths every year.
Having various levels of #physical contact with an #ill person can be enough to spread an #illness. #Premilife #DrRicardoKotliroff
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